ARA-290

ARA-290, also known as cibinetide, is a synthetic 15–amino-acid peptide derived from the Helix-B surface region of erythropoietin (EPO). Unlike EPO, ARA-290 does not activate the classical EPOR receptor pathway. In controlled laboratory research, it is examined for its selective interaction with the EPOR/CD131 heteromeric complex, also referred to as the innate repair receptor (IRR). Supplied as a lyophilized peptide powder, ARA-290 is intended exclusively for in-vitro laboratory research where high-purity peptide material is required.

Research Applications: (In-Vitro Use Only)

ARA-290 is studied in controlled laboratory settings for:

• Characterization of EPOR/CD131 (IRR) peptide–receptor interactions
• Analysis of selective signaling pathways related to cytokine modulation
• Investigations of structure–function relationships in EPO-derived peptides
• Binding, stability, and physicochemical profiling in peptide research
• Laboratory assays exploring pathway specificity and receptor selectivity

Storage and Handling:

• Store lyophilized powder at −20 °C
• After reconstitution, maintain at 2–8 °C
• Use promptly after reconstitution
• Handle using standard aseptic laboratory technique

Product Specifications:

• Purity: ≥99% (HPLC Certified)
• Appearance: Lyophilized white to off-white powder
• Solubility: Soluble in aqueous laboratory buffers; solubility varies with pH and medium

Compliance Notice:

ARA-290 is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.